Controlled-Rate Freezer

In order to maintain cellular viability during the freezing process, certain cells – such as protist, mammalian, and plant cells – require precise control of the freezing rate in order to minimize the detrimental effects of undercooling and the heat liberated during the phase change process from water to ice.

Controlled rate freezing is an established procedure for the cryopreservation of biologic material in research and clinical applications. In-line with GMP protocols, cell material can be frozen then stored at cryogenic temperatures.

CryoVita controlled-rate freezer (CRF) achieve reliable, reproducible results with maximum operational safety. They are used for clinical, veterinary and research tasks for controlled rate freezing of samples.


Dependable sample protection

For customers in research, cell and gene therapy, vaccine production, and biobanking, the CryoVita CRF provides precise, repeatable freezing results that protect the sample from intracellular freezing.

Liquid nitrogen flows via a metal hose connection, as a gas, into the freezing chamber. Predetermined cooling 

profiles are used to freeze samples prior to removal and storage at cryogenic temperatures. Data logging ensures continual monitoring of the entire process, including multiple temperature sensor set-points, actual values and the supply pressure of liquid nitrogen.

Reliable temperature performance for high-throughput usage

1.Dual solenoid valves design, one for working, the other for backup. When one valve fails, switch to the other 

valve through touch screen controller

2.Consistent temperature control and uniformity achieved via an air-handling system and liquid nitrogen injection device

3.Environmentally friendly insulating foam

4.Type 304 stainless steel with exterior powder-coat finish

User-friendly operation with enhanced data traceability


1.Intuitive touchscreen display allows for easy set-up, operation, and review of a freezing run

2.Six pre-set freezing profiles and space for up to 120 user-defined, “custom” freeze profiles

3.Convenient to create and edit a custom program on touch screen

4.Record temperature curve of each cycle automatically

5.External influences are avoided during freezing

 

Real-time run monitoring for sample protection

1.Chamber and sample temperatures are monitored by Type T thermocouples, eliminating lag time and providing “real time” responsiveness

2.Standard alarms to alert users of thermocouple failures, heater malfunction, high/low temperature limits, 

temperature tracking, power failure, and completion of run

3.RS232 Port

4.USB port to download running data

Installation

CryoCenter series self-pressurized liquid nitrogen 

Container is recommended to supply liquid nitrogen 

CryoVita series controlled rate freezers.

1.0.1MPa pressure 

2.Pressure building regulator

3.Liquid level meter (float type/ electric digital type) 

4.Casters for easy movement



ModelCryoVita 18CryoVita 34CryoVita 49
Door typeFront   open (upright)Front   open (upright)Front   open (upright)
Capacity   (Liter)183449
2ml vial3808051185
5ml vial228483711
25/50ml blood   bag306090
250ml blood   bag102030
500ml blood   bag81624
1/2 cc straw330660990
Interior dimensions
    W x D x H (mm)
180   x 305 x 330330   x 305 x 330485   x 305 x 330
Exterior dimensions
    W x D x H (mm)
810   x 540 x 790960   x 540 x 7901110   x 540 x 790
Net weight   (kg)647583
Heating power (W)250030003000
Power supply AC 100~240V, 50/60Hz
Interior materialSUS304
Door sealYes
Temperature range (°C)-180 ~ 50
Freezing rate (°C/min)0.1 ~ 60
Heating rate (°C/min)0.1 ~ 10
Temperature deviation (°C)<2
ControllerTouch screen & microprocessor
Freezing program storageUp to 20 (6 default programs)
Data storage and USB portYes
Chamber temperature displayYes
Sample sensor & temp displayYes
Freezing step displayYes
Running time displayYes
Remaining time displayYes
Door-operation safety interlockYes
RefrigerantLiquid nitrogen
Prefilter for liquid nitrogenYes
Liquid nitrogen source pressure14 ~ 22 PSI
Pressure relief valveYes, 125 PSI
Freezing racksOptional
ModelCryoVita 26HCryoVita 90HCryoVita 150H
Door typeTop   open (horizontal)Top   open (horizontal)Top   open (horizontal)
Capacity   (Liter)2690150
0.25ml   Straw 90027004500
0.5ml   Straw 63018903150
Interior dimensions
    W x D x H (mm)
476   × 184 × 340476   × 552 × 340476   × 767 × 380
Exterior dimensions
    W x D x H (mm)
701×   769× 539701×   1244 × 570711×   1444 × 584
Net weight   (kg)4062140
Heating power (W)250030003000
Power supply AC 100~240V, 50/60Hz
Interior materialSUS304
Door sealYes
Temperature range (°C)-180 ~ 50
Freezing rate (°C/min)0.1 ~ 50
Heating rate (°C/min)0.1 ~ 10
Temperature deviation (°C)<2
ControllerTouch screen & microprocessor
Freezing program storageUp to 20 (6 default programs)
Data storage and USB portYes
Chamber temperature displayYes
Sample sensor & temp displayYes
Freezing step displayYes
Running time displayYes
Remaining time displayYes
Door-operation safety interlockYes
RefrigerantLiquid nitrogen
Prefilter for liquid nitrogenYes
Liquid nitrogen source pressure14 ~ 22 PSI
Pressure relief valveYes, 125 PSI
Freezing racksOptional


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