Single chamber systems
- Compact design with highly efficient and economical operation.
- Excellent drying rates for sensitive materials and products with low eutectic points or low collapse temperatures.
- Built-in ice condenser shortens drying time and avoids vapor condensation in vacuum pump.
- Up to 8 external vials available as options.
Shelves
- Stainless steel shelf areas with silicone heat transfer fluid, providing excellent thermal conductivity.
- Pulse-type electronic expansion valve, featuring a wide regulation range, quick and precise control on shelf
temperature, and low energy consumption.
- The uniformity of different layers and a same layer is within 1°C.
- Hydraulic stopper system as standard.
Refrigeration & ice condenser
- Ice condenser temperature reaches -90°C.
- Built-in ice condenser coils for higher efficiency.
- Hot gas defrosting, quickly proceed to the next freeze-drying process.
- Mechanism door lock for convenient cleaning.
Vacuum control
The vacuum degree and duration of each step can be set and controlled at auto mode. Pirani vacuum gauge with accuracy 0.001mbar. Vacuum control reduced drying time by up to 40%.
Advanced Pirani vacuum gauge allows:
- Airtightness check: before freeze drying process, set a vacuum degree 600~950mbar to check airtightness.
- Gas backfill: after freeze-drying completed, set a vacuum degree 500~800mbar, to backfill inert gas, so that the vial can be plugged under a slightly negative pressure for a longer storage time.
Unique system LyoSMART+ controller
LyoSMART+ controller provides an easy-to-use and intuitive user interface.
All of the extensive accessories are also integrated. Reproducible results are assured by automatic process sequences.
Convenient and intuitive
- Color touchscreen with clear display.
- Automatic or manual mode.
- Intuitive program entry, using various freeze-drying sequences and recipes.
- Memory space for 30 user-defined programs with 36 steps.
- Real-time freezing drying diagram display, selective parameter display, data query & export.
- Set safety values such as vacuum level and resistivity for process feedback control.
- Password protection for startup and lock screen protection.
- Equipped with USB port & RS232 port.
PAT(Process Analytical Technology) Tools
Freezing point determination
- The LyoTR sensor monitors both electrical resistance andproduct temperature. From the curves of both of these variables, operator can determine the eutectic point and freezing point of product.
- The LyoTR sensor allows automated control of the energy supply to the shelves during the main drying phase to avoid critical temperatures during the main drying phase, which reduces product defrost risk.
Product Temperature Measurement
The product temperature influences the form of the ice structure and the speed of the freeze drying process, and it can initiate a thawing process. The product temperature is monitored during the measurement process.
The ultra-fine Pt100 probe with flexible wire harness is compact, highly resistant to interference, corrosion-resistant, and easy to calibrate.
Comparative pressure measurement (optional)
The end of the main drying phase can be detected by using two different vacuum measurement sensors: Pirani vacuum gauge and capacitive vacuum sensor.
When the difference between the pressure measurements falls below a preselected threshold, it indicates that main drying has concluded.
